?

Log in

No account? Create an account

October 11th, 2020

grapefruit is weird

https://www.atlasobscura.com/articles/grapefruit-history-and-drug-interactions

Article via conuly.

* citrus genetics were weird and messy, if you didn't know that already.

* grapefruit is a feral hybrid discovered in Barbados, halfway around the world from Citrus Central.

* As you should learn if you don't know already, grapefruit has lots of drug interactions. Seems that's indirect: grapefruit disables stomach enzymes that normally break down most of an oral medication, so if you take the drug within 12 hours of grapefruit, you get much more drug than the prescription calls for. It can also disable some drug transporter proteins that bring things (like drugs) into cells, so in those cases you get less drug than expected.

* Tylenol is one of the drugs, though I'm not sure which class. I assume the second, from the lack of more strident recommendations not to mix them, because it's already too easy to OD on Tylenol.

* All the bitter pomelo derivatives have that effect, but you're "unlikely" to consume enough lime or sour orange for it to hurt, and I assume sweet orange doesn't have enough pomelo heritage, or didn't inherit the right genes. See the comment count unavailable DW comments at https://mindstalk.dreamwidth.org/570103.html#comments

Tags:

Profile

Phoenix
mindstalk
Damien Sullivan
Website

Latest Month

December 2020
S M T W T F S
  12345
6789101112
13141516171819
20212223242526
2728293031  

Tags

Comments

  • 17 Aug 2019, 04:45
    I use Yardley's English Lavender soap, and a bar lasts a good long while.
  • 19 Sep 2018, 20:20
    The block south of me is the 400s, whereas mine has addresses like 17-11.

    Ah, gobbled up in the rift, no doubt.
  • 10 Sep 2018, 20:14
    The most systematic way I have is working through a tutorial for the language.

    A couple years ago I'd been working on what I called Language Reference Suites, which were big blobs of code doing…
  • 10 Sep 2018, 20:10
    No, but my roommates had a cat that would stalk and attack me.
  • 10 Sep 2018, 15:26
    Do you have some systematic way of learning a new coding language, or characterizing it for reference as you learn it?
Powered by LiveJournal.com
Designed by Lilia Ahner